Characterisation of the mitochondrial RNase P complex and associated diseases

Human mitochondrial RNase P protein 1 (MRPP1) and 2 (MRPP2) form a methyltransferase complex with N1-methylation activity towards purine-9 on mitochondrial tRNA. A third component, mitochondrial RNase P protein 3 (MRPP3), adds RNase P 5'-end ribonuclease processing activity to the complex. MRPP...

Full description

Bibliographic Details
Main Author: Oerum, Stephanie
Other Authors: Oppermann, Udo ; Yue, Wyatt W.
Published: University of Oxford 2016
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730227