The role of the cellular membrane environment in mediating fibrillization and toxicity of islet amyloid polypeptide
Islet amyloid polypeptide (IAPP) is a peptide that is produced by the beta cells in the pancreas. A misfolded, aggregated form of this peptide is associated with Type 2 Diabetes and is found as large brils in pancreata, intimately associated with the islet architecture. The role of these brils is th...
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University of Oxford
2016
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730309 |