Development of computational methodologies for antibody design

Antibodies are proteins of the adapative immune system. Structural diversity in an antibody's two variable domains, V<sub>H</sub> and V<sub>L</sub>, allow it to bind almost any molecule with high affinity and specificity. This thesis focuses on characterising such variat...

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Bibliographic Details
Main Author: Leem, Jinwoo
Other Authors: Deane, Charlotte M.
Published: University of Oxford 2016
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730368