Interleukin-6 promoter polymorphisms, chromatin remodelling and gene expression in a monocyte-derived macrophage model of inflammation
lnterleukin-6 (IL-6) is a pro-inflammatory cytokine produced by macrophages, endothelial cells, fibroblasts, vascular smooth muscle cells, T lymphocytes and adipocytes. IL-6 is regulated at the level of transcription. There are multiple regulatory elements in the IL-6 promoter. Three single nucleoti...
| Main Author: | |
|---|---|
| Published: |
University of Surrey
2007
|
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.731092 |