Investigating engrailed-2 (EN2) as a therapeutic target in prostate cancer
Engrailed-2 (EN2) is a transcription factor involved in development, where it has multiple functions and is expressed in a caudal-to-rostral gradient in the midbrain. Its mRNA and protein expression are absent from most adult cells, but are switched back on in cancer cells. Although transcription fa...
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University of Surrey
2017
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.731163 |