Elucidating molecular mechanisms of actinobacterial polyketide alkaloid biosynthesis
Coelimycin P1 is a yellow-pigmented alkaloid with a unique 1,5-oxathiocane ring, produced by Streptomyces coelicolor M145. Recently, it was demonstrated that a type I modular polyketide synthase (PKS) with a C-terminal thioester reductase (TR) domain is involved in its assembly. Due to its unusual b...
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University of Warwick
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.731420 |