Genotype-phenotype analysis of the checkpoint kinase MEC1, the budding yeast homologue of human ATM/ATR

The protein kinases ATR and ATM, and their Saccharomyces cerevisiae counterparts Mec1 and Tel1, are the apical kinases of the DNA damage response, a cellular response to potentially lethal DNA damage from both endogenous and exogenous sources. ATR/ATMMec1/Tel1 are part of the PIKK (PI3-kinase-like k...

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Bibliographic Details
Main Author: Waskiewicz, Erik
Other Authors: Cha, Rita
Published: Bangor University 2017
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.731725