Microglial TRPM2 channel activation and its relationship to neurodegenerative diseases

Microglial cell plays a key role in neuroinflammation induced by diverse danger associated molecular patterns (DAMP) molecules, such as Zn2+, Aβ42 and TNF-α, and strongly implicated in neurodegenerative diseases. The molecular mechanisms for neuroinflammation are however not fully defined. Reactive...

Full description

Bibliographic Details
Main Author: Syed Mortadza, Sharifah Alawieyah
Other Authors: Jiang, Lin Hua
Published: University of Leeds 2017
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733573