Microglial TRPM2 channel activation and its relationship to neurodegenerative diseases
Microglial cell plays a key role in neuroinflammation induced by diverse danger associated molecular patterns (DAMP) molecules, such as Zn2+, Aβ42 and TNF-α, and strongly implicated in neurodegenerative diseases. The molecular mechanisms for neuroinflammation are however not fully defined. Reactive...
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University of Leeds
2017
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733573 |