Characterization of UHRF2 (RNF107) as a novel sensor for DNA ICLs in the Fanconi Anemia pathway
The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA helix. An initial and essential stage in the repair process is the detection of the ICL. In a previous study, UHRF1 was identified as an ICL sensor in humans, it was s...
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University of Oxford
2017
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.735898 |