Characterisation of the component(s) responsible for the trypsin-like activity of the multicatalytic proteinase

The multicatalytic proteinase (MCP) is a 700 kDa multisubunit complex which is found in eukaryotic cells. MCP is involved in ubiquitin-dependent non-lysosomal protein degradation and has been implicated in the processing of antigens by the major histocompatability complex class 1 pathway. The MCP pu...

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Bibliographic Details
Main Author: Savory, Peter John
Published: University of Leicester 1992
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737399