Probing the structure and mechanism of DNA gyrase

DNA gyrase is the enzyme from bacteria which is unique among type II topoisomerases in its ability to introduce negative supercoils into DNA. The enzyme acts as an A2B2 tetramer of molecular weight 374 kDa. The supercoiling reaction of gyrase involves wrapping of DNA around the enzyme and the coupli...

Full description

Bibliographic Details
Main Author: Orphanides, George
Published: University of Leicester 1995
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737547