Quantifying biased agonism of adenosine and calcitonin-like receptors

G protein-coupled receptors (GPCRs) elicit an ability to activate multiple downstream signalling pathways. It is becoming evident that for many GPCRs, agonists are able to activate several of these pathways, each to differing extents; a phenomenon termed pathway bias, or biased agonism. Here, work i...

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Bibliographic Details
Main Author: Winfield, Ian J.
Published: University of Warwick 2017
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737750