The effects of environmental and microbiota manipulation on myelination in the YAC128 and BACHD models of Huntington disease

White matter (WM) deterioration is increasingly being recognised as a hallmark of Huntington disease (HD) and is correlated to disease severity. The research presented in this thesis employed environmental and microbiota manipulations as assays to interrogate white matter plasticity in two mouse mod...

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Bibliographic Details
Main Author: Radulescu, Carola Izabela
Other Authors: Pouladi, Mahmoud ; Vautrelle, Nicolas ; Bracci, Enrico ; Redgrave, Peter
Published: University of Sheffield 2017
Subjects:
150
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737872