Studies on the total synthesis of aphidicolin

In this thesis further developments on the thermal cascade reaction discovered in the Parsons group have been made. The substrate scope has been increased to include the ketone linked 1,6-diynes, which had failed to cyclise in previous studies. Furthermore, variations on the precursor molecule have...

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Bibliographic Details
Main Author: Allen, Lewis Alexander Thomas
Other Authors: Parsons, Philip James
Published: Imperial College London 2015
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.739554