The effects of hypomorphic STAT3 on lymphocyte function and intestinal immune regulation

Dominant-negative mutations in signal transducer and activator of transcription 3 (STAT3) underlie the human primary immunodeficiency autosomal dominant hyper IgE syndrome (HIES). A number of aspects of this disease, including the eponymous elevated serum IgE, remain poorly understood. Additionally,...

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Bibliographic Details
Main Author: Steward-Tharp, Scott
Published: University of Oxford 2012
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740782