The effects of hypomorphic STAT3 on lymphocyte function and intestinal immune regulation
Dominant-negative mutations in signal transducer and activator of transcription 3 (STAT3) underlie the human primary immunodeficiency autosomal dominant hyper IgE syndrome (HIES). A number of aspects of this disease, including the eponymous elevated serum IgE, remain poorly understood. Additionally,...
Main Author: | |
---|---|
Published: |
University of Oxford
2012
|
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740782 |