Investigating the cooperation of APC and KRAS mutations in colorectal cancer

Colorectal Cancer (CRC) progresses in a stepwise manner accumulating mutations in particular signalling pathways. Despite our knowledge of the genetic progression of the disease, the resulting phenotypes of the different mutation combinations remains poorly understood. I used genetically engineered...

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Bibliographic Details
Main Author: Gay, David Michael
Published: University of Glasgow 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744148