Heparin and heparin-like molecules inhibit the Alzheimer's β-secretase (BACE1) : considerations for biological assay and future therapeutic development
The biologically and medically important heparan sulphate and heparin polysaccharides have previously been shown to modulate the activity of an aspartyl protease, β-secretase (BACE1), implicated in the aetiology of Alzheimer’s disease. Research groups investigating the activity of heparin with BACE1...
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Keele University
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745337 |