Effect of DNA damage and repair mechanisms in human haematopoiesis and their role in chemoresistance of acute myeloid leukaemia
Most standard AML chemotherapy regimes utilize Ara-C, a cytotoxic compound inflicting DNA damage in proliferating cells and inducing cell death. Comparing normal and malignant haematopoietic cells in their response to Ara-C will determine whether differing responses to DNA damage and activation of D...
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University College London (University of London)
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.746445 |