Design and synthesis of chemical probes for the BRPF bromodomains
Bromodomains (BRDs) are protein-protein interaction modules responsible for recognition of and binding to ε-N-acetylated histone lysines. Following on from the success in drugging the Bromodomain and extra-terminal (BET) domain BRDs, there has been significant interest in elucidating the biological...
| Main Author: | |
|---|---|
| Published: |
University College London (University of London)
2017
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.746578 |