Assessment of fibroblast growth factor receptor cancer-associated mutations and characterisation of endocrine signalling complexes

Receptor tyrosine kinase (RTK) signalling is frequently deregulated in cancers, developmental syndromes and metabolic diseases. The fibroblast growth factor (FGF) receptor (FGFR) family of RTKs have pleiotropic roles in development, metabolism and tissue homeostasis. A decade of deep sequencing stud...

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Bibliographic Details
Main Author: Patani, Harshnira Hitesh
Published: University College London (University of London) 2018
Subjects:
500
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747511