Structure-function relationship of DEF6

DEF6 (Differentially Expressed in FDCP 6, also known as IBP and SLAT) is critical for the development of autoimmune disease and cancer. In T cells, DEF6 participates in TCR-mediated signalling determining T helper cell-mediated immune responses. In addition, DEF6 acts as a guanine nucleotide exchang...

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Bibliographic Details
Main Author: Cheng, Huaitao
Published: University of Nottingham 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748451