Investigation into synthetic amphiphilic polymers for intracellular delivery
Delivery of siRNA therapeutics to their target site within the cell interior is a challenge that hinders their effective use in disease treatment. PP-75, a pH-responsive polymer, demonstrates potential to enhance intracellular siRNA-delivery by overcoming endosomal entrapment. PP-75 also provides a...
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Imperial College London
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.749123 |