Investigating the role of two activating receptors, NKG2D and NKp46, in natural killer cell education and in the development of hepatocellular carcinoma linked to chronic inflammation

Natural killer (NK) cells are innate lymphocytes capable of identifying infected and tumourigenic cells and eliciting a cytokine and/or cytotoxic response. NK cells contain multiple activating and inhibitory receptors that bind to ligands expressed on other cells, and responses to abnormal cells are...

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Bibliographic Details
Main Author: Sheppard, Sam
Other Authors: Guerra, Nadia ; Davis, Daniel
Published: Imperial College London 2013
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.754634