Regulation of voltage-gated potassium (Kv) and two-pore domain potassium (K2P) channels implicated in pulmonary hypertension

Background: Kv2.1 and TASK-1 channels are two main contributors of K+ currents in pulmonary artery smooth muscle cells (PASMC). Dysregulation of these channels has been implicated in the pathogenesis of pulmonary hypertension (PH). This thesis aims to delve deeper into the implications of the regula...

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Bibliographic Details
Main Author: Lee, Mun Ching
Other Authors: Mathie, Alistair
Published: University of Kent 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.754834