Studying the effects of DNA replication stress on genome integrity and cell viability

Accurate replication of the genome during cell division is essential for maintaining genome integrity and suppressing diseases such as cancer. DNA replication forks can stall, collapse and/or break when they encounter obstacles present in DNA. This causes DNA replication stress, which is a major sou...

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Bibliographic Details
Main Author: Alhamoudi, Kheloud M. H.
Other Authors: Foster, Steven S.
Published: University of Leicester 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755319