A tale of two epigenetic protein pairs : characterizing the Sin3aTET1 complex and the decrotonylation activity of HDAC1/2

Characterizing the Sin3a-TET1 Complex: TET 1 permits active DNA demethylation, promoting a transcriptionally permissible environment by preventing aberrant methylation. Contrastingly, Sin3a is the scaffold-protein central to the eponymous co-repressor complex. Histone deacetylases 1 and 2 (HDACl/2)...

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Bibliographic Details
Main Author: Chandru, Aditya
Other Authors: Cowley, Shaun ; Eperon, Ian
Published: University of Leicester 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755369