The molecular basis of antagonism by PPADS at the human P2X1 receptor

P2X receptors (P2XRs) activated by ATP are widely expressed throughout the human body and mediate various physiological and pathophysiological roles. Crystal structures have provided a major advance in understanding agonist and subtype selective antagonist actions. However, the molecular basis of an...

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Bibliographic Details
Main Author: Huo, Hong
Other Authors: Evans, Richard ; Vial, Catherine
Published: University of Leicester 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755412