Mind the traffic : validation and characterisation of artemisinin resistance pathways in Plasmodium falciparum by genome editing
Artemisinin susceptibility in Plasmodium falciparum is modulated by mutations in the gene pfk13, which encodes a kelch propeller domain protein of unknown function. Reduced susceptibility is demonstrated in vitro by elevated parasite survival after short exposures to physiologic concentrations of dr...
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London School of Hygiene and Tropical Medicine (University of London)
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755889 |