Mechanisms of cancer evolution and drivers of tumour heterogeneity
Cancer drug resistance is almost inevitable in the majority of patients with advanced metastatic tumours. Intra-tumour heterogeneity, facilitating rapid tumour evolution, is a main cause of resistance to cancer therapies. In this thesis, I explore how cancer genome sequencing data can shed light int...
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University College London (University of London)
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.755981 |