Investigating the relationship between core stability and early life cycle events in HIV-1

HIV-1 capsid (CA) plays a vital role in the early stages of HIV-1 infection. The CA lattice surrounding the viral core is predominantly assembled from CA hexamers and stabilised by intra-hexamer and inter-hexamer interactions. Optimal stability of the lattice is known to be critical for efficient in...

Full description

Bibliographic Details
Main Author: Donaldson, Callum
Published: University College London (University of London) 2018
Subjects:
616
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756208