Preclinical atherosclerosis in monogenic familial hypercholesterolaemia and polygenic hypercholesterolaemia

Familial Hypercholesterolaemia (FH) is an autosomal dominant disorder with a frequency of 1 in 250 to 500 in most European populations. It is characterised by a raised low density lipoprotein-cholesterol (LDL-C) and a high incidence of premature coronary heart disease (CHD). There are three genes wh...

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Bibliographic Details
Main Author: Sharifi, Mahtab
Published: University College London (University of London) 2018
Subjects:
617
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756266