Genetic factors modulating mitochondrial DNA copy number

Mitochondria are dynamic organelles whose principal role is the generation of cellular energy (ATP) through oxidative phosphorylation (OXPHOS). 13 OXPHOS subunits are encoded by the mitochondrion’s polyploid circular genome (mtDNA), and the nuclear genome (nDNA) encodes the remaining subunits as wel...

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Bibliographic Details
Main Author: Brennan, Rebecca Ruth
Published: University of Newcastle upon Tyne 2017
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.757101