The application of mechanistic modelling as a tool in drug disposition and risk assessment

New molecular entities entering the pharmaceutical market are required to adhere to stringent safety, efficacy and quality requirements that often lead to delays in the early-phases of drug development. Pharmacokinetic modelling approaches, such as physiologically-based pharmacokinetic (PBPK) modell...

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Bibliographic Details
Main Author: Zakaria, Zaril Harza
Published: Aston University 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760161