Exploring the aetiology and phenotypic consequences of non-syndromic cleft lip/palate using polygenic risk scoring and Mendelian randomization
Non-syndromic cleft lip/palate (nsCL/P) is a congenital birth defect characterised by cleft(s) of the upper lip with or without a cleft of the palate. The aetiology of nsCL/P is complex with both genetic and environmental risk factors. In this thesis, I applied Mendelian randomization (MR) and polyg...
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University of Bristol
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.761098 |