Using the potent Pasteurella multocida toxin to probe G-protein signalling

The heterotrimeric G-proteins are critically important intracellular signalling molecules that regulate fundamental processes in cellular homeostasis. A unique bacterial toxin, Pasteurella multocida toxin (PMT) modifies 3 of the 4 families of G-proteins (Gq, Gi, and G12) by deamidation which leads t...

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Bibliographic Details
Main Author: Thompson, Cherrie Delos Santos
Other Authors: Lax, Alistair ; Grigoriadis, Agamemnon Emil
Published: King's College London (University of London) 2016
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762305