Investigating the role of mTOR signalling in mediating the pro-fibrotic effects of TGF-β1

Tissue fibrosis, for which there are at present limited therapeutic strategies, is characterised by abnormal wound healing responses resulting in excessive extracellular matrix (ECM) production, leading to significant tissue architecture distortion and impaired organ function. In the lung, fibrosis...

Full description

Bibliographic Details
Main Author: Eley, Jessica
Published: University College London (University of London) 2018
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763189