Deciphering the T cell receptor repertoire and immune checkpoint landscape in tumours with a high mutational load

The advent of checkpoint immunotherapy has revolutionised the treatment of solid cancers, resulting in durable responses in a number of patients. However the majority of patients do not respond to treatment, underscoring the need to better understand the mechanisms that underlie the immunological re...

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Bibliographic Details
Main Author: Joshi, Kroopa
Published: University College London (University of London) 2018
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763216