Modelling Parkinson's disease with α-synuclein transgenic mice

Parkinson's disease is a chronic, progressive, neurodegenerative movement disorder characterised by bradykinesia, tremor at rest, rigidity and postural instability. The pathological hallmark of the malady is a loss of dopaminergic nigrostriatal neurons, coupled with the inclusion of Lewy bodies...

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Bibliographic Details
Main Author: Scudamore, Owen
Other Authors: Wang, Xin
Published: University of Manchester 2013
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764268