Extended D-E knob-hole interaction sites in fibrin polymerisation, clot formation and clot mechanics
Background: Abnormal thrombus formation and occlusion of a vessel is one of the main events of cardiovascular disease. A main component of the thrombus is the protein fibrin, which is formed by proteolytic cleavage of its precursor fibrinogen by the serine protease thrombin. The cleavage of fibrinog...
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University of Leeds
2019
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766487 |