Developing a toolbox of Affimer reagents targeting SH2 domains to study protein-protein interactions in disease
Src Homology 2 (SH2) domains are phosphotyrosine-binding modules that mediate a range of protein-protein interactions. These domains are found in over 120 human proteins and are involved in several signalling pathways that can become deregulated in diseases such as cancer. Research into the role of...
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University of Leeds
2019
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766489 |