Modulation of the base excision repair (BER) pathway in the treatment of glioblastoma with radiotherapy
Glioblastoma is an aggressive brain cancer with a median survival rate of 14.6 months post diagnosis. Treatments for glioblastoma include surgery, radiotherapy, and chemotherapy with the alkylating agent temozolomide (TMZ). In 50% of patients, TMZ treatment is ineffective due to the reparative actio...
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University of Surrey
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.766969 |