Characterization of the human Pif1 helicase as a potential cancer-therapy target
Pif1 is a multifunctional 5´ → 3´ superfamily 1 (SF1) helicase that is conserved in eukaryotes and also some prokaryotes. In addition to unwinding activity, the protein is a G-quadruplex (G4) DNA binding protein and strand annealing enzyme. Eukaryotic Pif1 proteins have roles in mitochondrial and nu...
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University of Sheffield
2018
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.767265 |