DNA-dependent protein kinase as a therapeutic target in chronic lymphocytic leukaemia
The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) functions in the non- homologous endjoining (NHEJ) pathway of DNA double strand break (DSB) repair and is overexpressed and/or highly active in several cancers, including chronic lymphocytic leukaemia (CLL). CLL treatment options have...
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University of Newcastle upon Tyne
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.768490 |