Protein kinase C δ is a potential therapeutic target in malignant melanoma with NRAS mutation or B-RAF inhibitor-resistance
Thesis (Ph.D.)--Boston University === Metastatic melanoma is the major cause of skin cancer death, and the annual incidence of melanoma continues to increase. Despite the impressively high rates of response to BRAF inhibitors in patients with melanomas harboring BRAF mutations, most of these patient...
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| Language: | en_US |
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Boston University
2015
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| Online Access: | https://hdl.handle.net/2144/12236 |