The human Klotho VS variant: focus on the processing and function of the V, S and VS isoforms
Klotho (KL), an anti-aging protein, attracted interest in the aging field because of the dramatic phenotype of KL deficient mice and its connection to signaling pathways implicated in aging. The KLVS variant consists of the F352V (KLV) and C370S (KLS) substitutions. It was detected in genome wide a...
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| Language: | en_US |
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2015
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| Online Access: | https://hdl.handle.net/2144/13168 |