Effects of regulatory light chain phosphorylation on mutant and wild-type cardiac muscle myosin mechanochemistry

Cardiac muscle contraction is responsible for pumping blood throughout the body. The cyclical, ATP-hydrolysis dependent interaction of the myosin motor protein with filamentous actin drives muscle contraction. During this process the α-helical neck region of myosin acts as a lever arm, transmitting...

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Bibliographic Details
Main Author: Karabina, Anastasia Smaro
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/13939