Effects of regulatory light chain phosphorylation on mutant and wild-type cardiac muscle myosin mechanochemistry
Cardiac muscle contraction is responsible for pumping blood throughout the body. The cyclical, ATP-hydrolysis dependent interaction of the myosin motor protein with filamentous actin drives muscle contraction. During this process the α-helical neck region of myosin acts as a lever arm, transmitting...
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Language: | en_US |
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2016
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Online Access: | https://hdl.handle.net/2144/13939 |