Characterization of BK viral responses to the dual-PI3K/MTOR inhibitor dactolisib (NVP BEZ-235) in a renal cell culture model

BK virus (BKV) is a ubiquitous polyomavirus known to asymptomatically reside in the renal tissues of up to 90% of the human population. BK virions reactivate during periods of intense immunosuppression and can cause disease in renal transplant recipients, such as BKV-associated nephropathy (BKVAN)....

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Bibliographic Details
Main Author: Lerner, Gabriel B.
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/14331