Defining mechanisms directing YAP/TAZ-mediated tumorigenesis
Dysregulated Hippo pathway signaling promotes the onset of aggressive cancers through the induced nuclear activity of yes-associated protein (YAP) and transcriptional co-activator with PDZ binding motif (TAZ) (YAP/TAZ). Uncontrolled nuclear YAP/TAZ activity evokes tumor-initiating properties in a ra...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/14589 |