Modulation of vascular endothelial growth factor receptor affinity by neuropilin-1 and heparan sulfate proteoglycans

Angiogenesis is a highly regulated process orchestrated by the vascular endothelial growth factor-A (VEGF-A) system of ligands and receptors. Heparin/heparan sulfate (HS) proteoglycans and neuropilin-1 (NRP-1) have been identified as co-receptors for VEGF-A, yet the mechanisms of action have not bee...

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Bibliographic Details
Main Author: Teran, Madelane
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/14590